While Meiko remains traumatized by Meicoomon's betrayal, Izzy becomes irritable as he obsessively tries to determine what caused Meicoomon to become infected. Meanwhile, as disruptions believed to be caused by Meicoomon start affecting airlines, Himekawa and Nishijima tell Matt about their investigation, but keep quiet about both Meicoomon causing the disruptions and the fact other DigiDestined have gone missing. Later, TK discovers something amiss with Patamon when he briefly acts violent and bites him. As TK decides to take Patamon home with him, prompting the others to do the same with their Digimon, he tells Meiko about what is really happening to Patamon, who eventually realises he is infected himself and asks TK to stop him should the worst come to happen. One night, a mysterious message appears all over electrical devices during a power outage, stating that "the Digimon will be released again". The next day, as Patamon informs the other Digimon about his infection, Kari becomes possessed by the mysterious messenger, Homeostasis, who warns them that the infected Digimon could potentially destroy both the Human and Digital Worlds unless a great sacrifice is made. Having overheard the whole thing, Himekawa reveals that the next Meicoomon appears, Homeostasis might trigger a "reboot", which would reset the Digital World to before the infection in order to save all other worlds. After Gatomon tells the others that this reboot would also cause them to lose all memories of their partners, the Digimon prepare for the worst and spend some precious time with their partners, during which Agumon tells Tai about the reboot. Izzy discovers that the distortions are the result of binary code being overwritten by a different language, coming up with a plan after Tentomon informs him about the reboot. Meicoomon soon appears again, prompting the Digimon to fight against her to try and keep her out of the Human World. Despite TK's attempts to stop him, Patamon digivolves to Angemon and enters the fray and becomes overpowered by his infection, which soon starts spreading to the other Digimon. As a countdown towards the reboot begins, Izzy brings up his counter-plan, creating a field that can use backup data to restore the infected Digimon. As Tentomon struggles with helping the others while fighting off his own infection, he digivolves into his Mega form, HerculesKabuterimon, captures Meicoomon and snaps the Digimon out of their infection before using all of his strength to push them back into the distortion before the reboot occurs. One week later, as the Digidestined decide they want to see their Digimon again, Meiko tells TK that the infection originated from Meicoomon, who was already infected the moment she met her, feeling she has no right to go see her. Using the power of their Crests, the DigiDestined travel to the rebooted Digital World, where they briefly encounter Alphamon fighting against another Mega-level Digimon named Jesmon. They soon come across their partner Digimon, who have lost their memories, deciding to befriend them from scratch. Meanwhile, as Himekawa confronts the Digimon Emperor, who is revealed to be Gennai, Meicoomon is seen nearby, still possessing her memories of Meiko.